High Frequency of OXA-253-Producing Acinetobacter baumannii in Different Hospitals in Recife, Brazil.

نویسندگان

  • Felipe Lira de Sá Cavalcanti
  • Carina Lucena Mendes-Marques
  • Crhisllane Rafaele Dos Santos Vasconcelos
  • Túlio de Lima Campos
  • Antonio Mauro Rezende
  • Danilo Elias Xavier
  • Nilma Cintra Leal
  • Osvaldo Pompilio de-Melo-Neto
  • Marcia Maria Camargo de Morais
  • Tereza Cristina Leal-Balbino
چکیده

Here, we report the isolation of 31 Acinetobacter baumannii strains producing OXA-253 in a single large Brazilian city. These strains belonged to five different sequence types (STs), including 4 STs not previously associated with blaOXA-253 In all strains, the blaOXA-253 gene was located in a plasmid within a genetic environment similar to what was found previously in Brazil and Italy. The reported data emphasize the successful transmission of the blaOXA-253 gene through a large area and the tendency for this resistance determinant to remain in the A. baumannii population.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

First report of OXA-143-lactamase producing Acinetobacter baumannii inQom

Objective(s):Antibiotic resistance in Acinetobacter baumannii and outbreaks caused by this organism have been reported from several areas of the world. The present study aimed at determining the antibiotic susceptibility profiles and the distribution of OXA-type beta-lactamases among Iranian Acinetobacter baumannii isolates from Qom of Iran. Materials and Methods: For this study, 108 non-duplic...

متن کامل

OXA-253, a variant of the carbapenem-hydrolyzing class D β-lactamase OXA-143 in Acinetobacter baumannii.

The carbapenem-hydrolyzing class D β-lactamase OXA-253 was identified in an Acinetobacter baumannii clinical isolate belonging to sequence type 113 (ST113) in Brazil. OXA-253 shares 93.8% amino acid identity with OXA-143. The blaOXA-253 gene is located on a ca. 20-kb plasmid. The genetic environment of the blaOXA-253 gene shares the highest identity with ubiquitous GR2 group plasmids usually ca...

متن کامل

Role of Aders and OXA23 Genes among Imipenem Resistant Acinetobacter baumannii Isolates from Two Hospitals of Tehran, Iran

Background: This study aimed to evaluate the role of efflux pump regulator and OXA-23 genes in imipenem resistance Acinetobacter baumannii strains isolated from hospitalized patients in Tehran, Iran. Methods: This study was conducted on 60 A. baumannii isolates collected from pa...

متن کامل

Emergence of Acinetobacter baumannii ST730 carrying the bla OXA-72 gene in Brazil

Over the last decade, Acinetobacter baumannii resistant to carbapenems has emerged in many medical centres and has been commonly associated with high morbimortality. In Brazil, this resistance is mainly attributed to the spread of OXA-23-producing clones and, to a lesser extent, to OXA-143-producing clones. Here, we describe, for the first time, two OXA-72-producing A. baumannii isolates in sou...

متن کامل

Detection of Integrons in Acinetobacter Baumannii Strains Isolated from the Nosocomial Infections of Ahvaz City and their Relation with the Resistance Pattern

Background and Aims: Acinetobacter baumannii is regarded as an important nosocomial pathogen around the world, especially in the intensive care unit that today seems to be resistant to the most antibiotics. Therefore, this study aimed to trace classes 1, 2, and 3 integrin in the isolates resistant to Acinetobacter baumannii. Materials and Methods: In this descriptive study, Acinetobacter bau...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 61 1  شماره 

صفحات  -

تاریخ انتشار 2017